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目的:分析绝经妇女卵巢肿瘤的临床及病理特征,探讨其诊断与治疗方法。方法:对经手术确诊的148例>45岁绝经妇女卵巢肿瘤患者的临床资料及病理结果进行回顾性分析。结果:148例患者中31例有腹痛,23例有腹胀,15例自觉有腹部包快,15例有绝经后阴道出血,45例有腰酸、下腹部坠胀感或阴道流液等非特异性症状,19例无症状;恶性47例,占31.8%,交界性5例,占3.4%,良性肿瘤96例,占64.9%;恶性和交界性肿瘤糖类蛋白-125和糖类蛋白-199均明显高于良性肿瘤(P<0.05),恶性肿瘤患者甲胎蛋白和癌胚抗原阳性率显著高于交界性和良性肿瘤患者(P<0.05);恶性肿瘤超声显像多为实性、囊实性或直径>10cm。结论:绝经后卵巢肿瘤临床表现隐匿,恶性比例较高,应定期妇科检查,结合肿瘤标记物和影像学特征,以早期诊断和手术治疗。
OBJECTIVE: To analyze the clinical and pathological features of ovarian tumors in postmenopausal women and to discuss its diagnosis and treatment. Methods: The clinical data and pathological findings of 148 patients with ovarian cancer diagnosed by surgery at the age of 45 were analyzed retrospectively. Results: Among the 148 patients, 31 had abdominal pain, 23 had abdominal distension, 15 had spontaneous abdomen fasting, 15 had vaginal bleeding after menopause, 45 had nonspecific symptoms of backache, lower abdominal bulge or vaginal fluid , 19 asymptomatic; malignant 47 cases, accounting for 31.8%, borderline 5 cases, accounting for 3.4%, 96 cases of benign tumors, accounting for 64.9%; malignant and borderline tumors of carbohydrate protein -125 and carbohydrate protein -199 were significantly (P <0.05). The positive rates of α-fetoprotein and carcinoembryonic antigen in patients with malignant tumors were significantly higher than those in borderline and benign tumors (P <0.05). The ultrasonographic findings of malignant tumors were mostly solid and cystic solid Or diameter> 10cm. Conclusion: Clinical manifestations of postmenopausal ovarian cancer hiding, a higher proportion of malignant, gynecological examination should be regular, combined with tumor markers and imaging features to early diagnosis and surgical treatment.