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许多多囊卵巢综合征(PCOS)单用克罗米芬疗效并不理想,使用hMG或FSH其排卵率与妊娠率均有改善,副作用是容易发生重症卵巢刺激综合征(OHSS)及多胎。现研究探讨GnRHa并用hMG对PCOS诱导排卵及预防OHSS的效果。PCOS的GnRHa/hMG/hCG疗法(并用疗法):从月经或孕酮引发撤退性出血的第2天开始,给予GnRHa 900μg/日点鼻,两周后加投hMG150IU/日,4~5天时在阴道B超下监测卵泡,在优势卵泡达18mm时,停用GnRHa及hMG,并一次性给予hCG5000IU。hMG/hCG疗法(单用疗
Many polycystic ovary syndrome (PCOS) with clomiphene alone is not ideal, with hMG or FSH its ovulation rate and pregnancy rates have improved, side effects are prone to severe Ovarian Stimulation Syndrome (OHSS) and multiple births. The study is to investigate the effect of GnRHa and hMG on ovulation induced by PCOS and prevention of OHSS. PCOS GnRHa / hMG / hCG Therapy (Combination Therapy): Starting from day 2 of menstruation or progesterone-induced withdrawal bleeding, GnRHa 900 μg / day was administered nose, hMG 150 IU / day after two weeks and 4-5 days Vaginal B ultrasound monitoring of follicles in the dominant follicle up to 18mm, disable GnRHa and hMG, and a one-time give hCG5000IU. hMG / hCG therapy (single therapy