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目的:分析中老年人群肥胖与牙周炎症的相关性。方法:选择天津市某社区51~88岁中老年人321名,收集一般和全身情况信息,根据体质量指数将321名中老年人分成正常(124)、超重(136)、肥胖(61)3组,检测其血常规、总胆固醇、甘油三酯、低密度和高密度脂蛋白胆固醇等指标,检查牙周指标以及血清B细胞活化因子(BAFF)水平并进行统计分析。结果:3组人群的基本情况无差异,血常规指标均在正常范围内。空腹血糖、甘油三酯、总胆固醇、低密度脂蛋白及牙周指标中的菌斑指数、探诊深度、附着丧失在3组间无差异(P>0.05);而牙周出血指数、血清BAFF水平,肥胖组较正常组高(P<0.05);出血指数与BAFF水平呈正相关(P<0.05)。结论:中老年人群中肥胖促进牙周炎症,血清BAFF可能参与了牙周炎症的调节过程。
Objective: To analyze the correlation between obesity and periodontal inflammation in middle-aged and elderly people. Methods: A total of 321 middle-aged and elderly people aged 51-88 years in a community of Tianjin were selected to collect general and systemic information. According to the body mass index, 321 middle-aged and elderly people were divided into normal (124), overweight (136), obesity The blood samples, total cholesterol, triglyceride, low density and high density lipoprotein cholesterol were detected. The periodontal index and the serum level of B-cell activating factor (BAFF) were detected and analyzed statistically. Results: There was no difference in the basic conditions among the three groups of patients, and the blood routine indexes were within the normal range. Fasting plasma glucose, triglyceride, total cholesterol, low density lipoprotein and periodontal index in plaque index, probing depth, loss of attachment was no difference between the three groups (P> 0.05); while the periodontal bleeding index, serum BAFF (P <0.05). Hemorrhage index was positively correlated with BAFF level (P <0.05). Conclusion: Obesity promotes periodontal inflammation in middle-aged and elderly people. Serum BAFF may be involved in the regulation of periodontal inflammation.