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该文作者研究了43例儿童慢性自身免疫性甲状腺炎(CLT)临床经过特点及随访3～20年结果。其中有29个家庭第一级亲属中(多数是母亲)罹患各种甲状腺疾病:弥漫性中毒性及非中毒性结节性甲状腺肿和 CLT。甲状腺肿大是 CLT 最初的临床表现,疾病进展缓慢,无任何自觉症状。在学龄前发现Ⅰ～Ⅱ度弥漫性甲状腺肿者21例,低年组学龄儿童10例,其中多数经2～8年观察,被内分泌科及儿科医师诊断为Ⅱ～Ⅲ度弥漫性甲状腺肿(甲状腺功能正常),其余12例在青春期发现Ⅱ一Ⅲ度弥漫性甲状腺肿。根据病史资料及临床经过特点,将患者分为两
The authors studied the clinical characteristics of children with chronic autoimmune thyroiditis (CLT) and the follow-up of 3 to 20 years. Thirty-nine of the first-degree relatives of the family (mostly mothers) suffered from various thyroid diseases: diffuse toxic and nontoxic nodular goiter and CLT. Goiter is the first clinical manifestation of CLT, the disease progressed slowly, without any symptoms. 21 cases of gradeⅠ ~ Ⅱ degree diffuse goiter and 10 cases of school age children in lower age group were found in preschool age. Most of them were observed in 2-8 years and were diagnosed as diffuse goiter Ⅱ ~ Ⅲ degree by endocrinology and pediatricians Thyroid function is normal), the remaining 12 cases found in adolescence Ⅱ a Ⅲ degree diffuse goiter. According to medical history and clinical characteristics, the patients were divided into two