论文部分内容阅读
为了阐明Ph′阳性的慢性粒细胞白血病(CML)急变时受累白血病细胞的起源和特性,作者对两例经临床、血液学、细胞遗传学所证实的Ph′阳性CML急性变患者的单一集落细胞同时进行了形态和核型检测。材料和方法例1,男性,56岁,初诊后31个月发展为典型的急粒变。例2,男性,53岁,初诊后4个月发展为嗜碱性粒细胞急性交。两例患者于急变期多次抽取外周血和骨髓。结果两例细胞经在体外甲基纤维素内集落培
In order to elucidate the origin and characteristics of leukemic cells involved in the acute phase of Ph ’-positive chronic myeloid leukemia (CML), we performed a retrospective study of two single colony-derived cells (PBMCs) that had been clinically, hematologically, cytogenetically proven in patients with acute PhC-positive CML At the same time the morphology and karyotype detection. Materials and Methods Example 1, male, 56 years old, developed 31 months after first visit as typical acute catgut infection. Example 2, male, 53 years old, 4 months after initial diagnosis of basophil acute cross. Two patients in the blastic phase multiple extraction of peripheral blood and bone marrow. Results Two cases of cells were cultured in vitro with methylcellulose