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[目的]了解连云港地区2007年预防接种后不良反应(AEFI)发生情况,以便能更好处理这些反应,减少AEFI的发生。[方法]对连云港市2007年AEFI监测报告的数据进行统计分析。包括预防接种后的一般反应或异常反应等按规定时限网络直报的汇总数据,并依照描述性流行病学方法,描述其各方面的分布情况以进行分析。[结果]在所统计的数据中,共报告AEFI162例,报告涉及17种疫苗,其中全细胞百白破疫苗(DTP)AEFI发生构成比最高占23.46%,乙肝疫苗AEFI的发生构成比居其次为18.52%。地区分布方面,各县区均有报告,其中东海县、赣榆县报告数共为71例,接近全市报告总数的一半。临床诊断中,以发热(包括轻、中、重度)和红肿浸润(包括弱、中、强度)较多,分别占总数的24.07%、26.54%。一般反应108例,占总报告人数的66.67%,异常反应54人,占总报告人数的33.33%。[结论]预防接种不良反应发生跟诸多因素有关,多数具有相似和较为典型的症状,多种疫苗均可以发生,不同疫苗的发生率不同,无明显的地区差异性,需更多的结合具体发生情况采取相对的措施以降低其发生。
[Objective] To understand the incidence of post-vaccination adverse reactions (AEFI) in Lianyungang in 2007 in order to better handle these reactions and reduce the occurrence of AEFI. [Method] The data of AEFI monitoring report in Lianyungang City in 2007 were statistically analyzed. Including aggregated data on networked reporting by regular deadlines, such as general or post-vaccination inaccuracies, and the descriptive epidemiological approach to describe the distribution in all its aspects for analysis. [Results] A total of 162 cases of AEFI were reported in the statistical data. The report involved 17 kinds of vaccines. Among them, the highest proportion of AEFI was 23.46%, and the incidence of AEFI of hepatitis B vaccine was secondly 18.52%. In terms of geographical distribution, all counties and districts reported that there were 71 reported cases in Donghai County and Ganyu County, nearly half of the total reported by the city. In clinical diagnosis, fever (including light, moderate and severe) and infiltration of inflamed (including weak, medium and strong) were more, accounting for 24.07% and 26.54% of the total, respectively. The general reaction of 108 cases, accounting for 66.67% of the total number of reports, anomalous reaction of 54 people, accounting for 33.33% of the total number of reports. [Conclusion] The incidence of adverse reactions of vaccination is related to many factors, most of them have similar and typical symptoms, many kinds of vaccines can occur, the incidence rates of different vaccines are different, there is no obvious regional difference and more need to be combined with specific occurrence The situation takes relative measures to reduce its occurrence.