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目的分析大肠癌(结肠癌和直肠癌)伴肝转移行同期切除影响患者预后的相关因素。方法采用多因素回归分析方法回顾性分析3 7例大肠癌伴肝转移患者行同期切除的临床资料;选取11项相关因素进行分析。结果年龄,门静脉化疗泵内局部化疗,组织学分型,淋巴结转移,肝转移灶位置,大小,数目对患者的生存时间有影响。结论大肠癌伴肝转移行同期切除术中术后行门静脉化疗泵内局部化疗可以改善患者的预后,延长其生存期,并且后者是惟一可控因素。
Objective To analyze the related factors that influence the prognosis of patients with colorectal cancer (colon cancer and rectal cancer) with hepatic metastases resection. Methods The multivariate regression analysis was used to analyze the clinical data of 37 cases of colorectal cancer with liver metastases undergoing resection in the same period. 11 related factors were selected for analysis. Results Age, local chemotherapy in the portal vein chemotherapy pump, histological type, lymph node metastasis, location of liver metastases, size and number had an impact on the patients’ survival time. Conclusions Chemotherapy of portal vein chemotherapy in patients with colorectal cancer with hepatic metastasis and concurrent resection can improve the prognosis and prolong the survival of patients after operation, and the latter is the only controllable factor.