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目的探讨降钙素原检测及C-反应蛋白检测两种方法对诊断新生儿感染疾病的临床价值。方法选择2012年1月—2014年11月商丘市妇幼保健院收治的120例新生儿感染病例,按感染程度分为重度感染组(56例)与局部感染组(64例),再选择同期50例健康新生儿作为对照组。给予三组新生儿降钙素原及C-反应蛋白检测,比较各组情况。结果重度感染组的降钙素原及超敏C反应蛋白水平显著高于局部感染组与对照组(P<0.05),局部感染组的显著高于对照组(P<0.05)。结论降钙素原及超敏C反应蛋白水平是检测新生儿感染的重要指标。
Objective To investigate the clinical value of procalcitonin and C-reactive protein in the diagnosis of neonatal infectious diseases. Methods 120 cases of neonatal infections admitted to Shangqiu MCH in January 2012-November 2014 were divided into severe infection group (56 cases) and local infection group (64 cases) according to the degree of infection, and then selected the same period of 50 Healthy neonates as a control group. Three groups of neonatal procalcitonin and C-reactive protein were detected, and the situation of each group was compared. Results The levels of procalcitonin and high sensitive C reactive protein in severe infection group were significantly higher than those in local infection group and control group (P <0.05), and those in local infection group were significantly higher than those in control group (P <0.05). Conclusions Procalcitonin and high-sensitivity C-reactive protein levels are important indicators of neonatal infection.