论文部分内容阅读
目的了解河南省驻马店市“艾滋病病毒(HIV)单阳”家庭阴性配偶HIV、病毒性乙型肝炎(乙肝)病毒(HBV)、病毒性丙型肝炎病毒(HCV)及梅毒感染现状及合并感染现状。方法采用普查方法,对河南省驻马店市“HIV单阳”家庭阴性配偶进行血清流行病学调查,采集阴性配偶的血标本,检测其HIV、HBV、HCV及梅毒感染状况。结果本次调查共采集“HIV单阳”家庭中HIV抗体阴性配偶血样3619份,经检测HIV抗体阳性49例,HIV感染率为1.35%,抗-HCV感染率为31.20%,且随着年龄的增加而逐步升高(趋势χ2=-3.78,P<0.01)、梅毒感染率为0.17%,但女性感染率高于男性(χ2=0.0061,P<0.01)、乙肝表面抗原(HBsAg)感染率为5.40%、乙肝“大三阳”[HBsAg、乙肝病毒e抗原(HBeAg)、乙肝病毒核心抗体(抗-HBc)]阳性率为0.77%,乙肝“小三阳”(HBsAg、抗-HBe、抗-HBc)阳性率为2.93%。HBsAg/HCV合并感染率最高为1.22%。HIV阳性者中,合并感染人数占的63.27%。结论驻马店市“HIV单阳”家庭阴性配偶的HIV感染率较高,已成为HIV感染的高危人群之一,4种传染病存在混合感染现象,建议加强对该人群的随访,定期检测HIV、HBV、HCV及梅毒,以控制4种传染病家庭内经性传播。
Objective To investigate the prevalence and merger of HIV, hepatitis B virus (HBV), viral hepatitis C virus (HCV) and syphilis in HIV-positive and HIV-negative families in Zhumadian, Henan Province. Infection status. Methods By means of census, the seroprevalence of HIV negative single spouse was investigated in Zhumadian City of Henan Province. The blood samples of negative spouses were collected to detect the infection status of HIV, HBV, HCV and syphilis. Results A total of 3619 HIV-negative maternal blood samples were collected from families with HIV single positives in this survey. Among them, 49 cases were positive for HIV antibody test, the HIV infection rate was 1.35% and the anti-HCV infection rate was 31.20% (Χ2 = -3.78, P <0.01). The infection rate of syphilis was 0.17%, but the infection rate of female was higher than that of male (χ2 = 0.0061, P <0.01). The infection of hepatitis B surface antigen The positive rates of HBsAg, HBeAg and HBc were 0.77% and 5.40%, respectively. The positive rates of HBsAg, HBsAg, Anti-HBe, anti-HBc) positive rate of 2.93%. The highest infection rate of HBsAg / HCV was 1.22%. Among HIV-positive persons, the number of co-infected persons accounted for 63.27%. Conclusions The negative HIV infection rates of negative couples with HIV single positive family in Zhumadian city have become one of the high risk groups of HIV infection. Four kinds of infectious diseases have mixed infection. It is suggested to strengthen the follow-up of this group and to regularly test HIV , HBV, HCV and syphilis to control sexual transmission within four families of infectious diseases.