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麻疹是儿科中常见呼吸道传染病之一,目前尚无有效药物治疗.我院近年来采用双黄连粉针剂治疗小儿麻疹,获得较满意效果,现报告如下.1 一般资料 1993年3～4月间收治麻疹住院病人62例,其中男38例.女24例;年龄最大14岁,最小4个月.诊断标准参照《实用儿科学》.病儿住院期间常规进行胸片、心电图、麻疹抗体IgM检测.62例中合并肺炎21例,喉炎2例,心肌炎3例,脑炎1例.随机分为双黄连粉针剂治疗组35例和病毒唑治疗组27例.2 治疗方法 治疗组入院后用双黄连粉针剂60mg/kg/日,溶于10%葡萄糖注射液中配制成1%浓度静滴,日1次.对照组入院后予病毒唑10～15mg/kg/次,加入适量10%葡萄糖注射液中静滴,每日1次.2组疗程均为5～7天,合并肺炎、喉炎者,疗程可适当延长,同时加用常规剂量青霉素或先锋霉素V抗感染.3 疗效观察指标 以入院后热退日、皮疹消退日、咳嗽消除日、肺部罗青消失日和住院日为观察指标.4 结果 见下表.
Measles is one of the common respiratory diseases in pediatrics, there is no effective drug treatment. In recent years, our hospital Shuanghuanglian powder injection treatment of measles in children, obtained more satisfactory results, are as follows.1 General information March-April 1993 Inpatients with measles admitted 62 cases, of which 38 males and 24 females, the oldest 14 years old, minimum 4 months diagnostic criteria with reference to “practical pediatrics.” Sick children during hospitalization routine chest X-ray, ECG, measles antibody IgM test .62 cases of pneumonia in 21 cases, laryngitis in 2 cases, myocarditis in 3 cases, 1 case of encephalitis were randomly divided into Shuanghuanglian injection group 35 cases and ribavirin treatment group 27 cases.2 treatment group after admission Shuanghuanglian injection 60mg / kg / day, dissolved in 10% glucose injection formulated as intravenous infusion of 1%, day 1. The control group after admission to ribavirin 10 ~ 15mg / kg / time, adding the right amount of 10% glucose Injection intravenous, day 1. 2 groups of treatment are 5 to 7 days, with pneumonia, laryngitis who can be an appropriate course of treatment extended, while adding conventional doses of penicillin or Vanguard ADM anti-infection.3 Observation of efficacy Indications to recuperate after admission, rash subsided day, cough elimination day, lung Luoqing disappeared Day and hospitalization days were observed.4 The results are shown in the table below.