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目的 :探讨硫酸镁辅助治疗难治性癫痫的剂量、方法及疗效。方法 :治疗组 46例 ,常规抗癫痫药物治疗同时加用 16.5 %硫酸镁 10ml口服 ,对照组 2 3例给予常规抗癫痫药物 ,卡马西平或苯妥英钠加苯巴比妥或氯硝西泮加用γ -氨基丁酸等治疗。结果 :治疗组有效率 84.78% ,对照组有效率 43 .48%。两组比较经统计学分析 P <0 .0 1,差异极显著。结论 :硫酸镁联合一线抗癫痫药治疗方法简单易行 ,具有良好效果
Objective: To investigate the dose, method and efficacy of magnesium sulfate in the treatment of refractory epilepsy. Methods: The treatment group, 46 cases of conventional antiepileptic drugs plus 16.5% magnesium sulfate 10ml orally, the control group of 23 patients given conventional antiepileptic drugs, carbamazepine or phenytoin plus phenobarbital or clonazepam plus With γ - aminobutyric acid and other treatment. Results: The effective rate was 84.78% in the treatment group and 43.48% in the control group. The two groups by statistical analysis of P <0. 01, the difference was significant. Conclusion: Magnesium sulfate combined with first-line anti-epileptic drugs is simple and easy to treat with good results