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人类免疫缺陷病毒(HIV)又称为人嗜T淋巴细胞病毒Ⅲ型(HTLV-Ⅲ),是AIDS发病的原因,本病可由输血、性接触及使用被污染的针头而感染,围产期内被感染的母亲可传染给新生儿。白血病患者在治疗过程中,因多次接受输血可存在这种危险因素。最近,我院发现4例持续完全缓解而长期存活的病人,表现为不明原因发热、体重下降、腹泻和皮肤淋巴结病,检查血清抗HIV抗体阳性。因此,我们对1978～1986年237例白血病患者中存在的HIV抗体作了回顾性研究。
Human immunodeficiency virus (HIV), also known as human T-lymphotropic virus type III (HTLV-III), is the cause of AIDS, which can be caused by transfusions, sexual contact and the use of contaminated needles. During the perinatal period Infected mothers can be transmitted to newborns. Leukemia patients in the course of treatment, due to multiple transfusion may exist this risk factor. Recently, 4 patients with persistent and complete remission and long-term survival were found in our hospital. Their manifestations were unexplained fever, weight loss, diarrhea and cutaneous lymphadenopathy. Serum anti-HIV antibody was tested positive. Therefore, we retrospectively reviewed the presence of HIV antibodies in 237 leukemia patients from 1978 to 1986.