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Stictaceae 科某些地衣的水溶性多糖对小白鼠肉瘤180有抗癌活性。本文重点研究了 Lobariaorientalis 的抗癌活性多糖。L.orientalis 的粉末依次用乙醚和80%乙醇提取以除去杂质后,以水在沸水浴上提取,于热滤液中加乙醇使产生沉淀,离心收集沉淀物,用乙醇和乙醚洗涤,干燥,得淡棕色粉末状多糖(LOF-1部位),对小白鼠肉瘤180有显著抑制作用。该粗制多糖通过葡聚糖 G-200凝胶柱层析,得到三个部位,其中 LOF-1和 LOF-2对小白
Water-soluble polysaccharides from some lichens of the Stictaceae family have antitumor activity against murine sarcoma 180. This article focuses on the antitumor activity of Lobariaorientalis polysaccharides. After the powder of L. orientalis was extracted with ether and 80% ethanol in order to remove impurities, it was extracted with water on a boiling water bath, ethanol was added to the hot filtrate to produce a precipitate, the precipitate was collected by centrifugation, washed with ethanol and diethyl ether and dried to give Light brown powder polysaccharide (LOF-1 site), the mouse sarcoma 180 has a significant inhibitory effect. The crude polysaccharides by G-200 dextran gel column chromatography to obtain three parts, including LOF-1 and LOF-2 of white