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目的 探讨多原发性肺癌特点。方法 检索 1981年 1月～ 1999年 6月在我院手术治疗的肺癌病人46 38例 ,其中 31例病理确诊为多原发性肺癌 ,占 0 .6 7%。结果 31例中第一、二原发肺癌以 5 0～ 6 5岁发病率最高 ,分别占 6 4.5 %和 6 8.2 %。 6 4个原发癌中鳞癌占 5 4.7%。同时癌、异时癌、同时异时癌分别占 2 9%、6 4.5 %及6 .5 %。X线显示 :6 4个原发癌以周围型多见 ,占 71.9%。 ～ 期为 84.4%。异时癌第二原发癌术后 5年生存率占 2 2 .7% (5 / 2 2 )。结论 多原发性肺癌易发生于老年人 ,病变多为早期 ,鳞癌多见 ,第二原发癌术后 5年生存率低。
Objective To investigate the characteristics of multiple primary lung cancers. Methods From January 1981 to June 1999, 4638 patients with lung cancer were treated surgically in our hospital. Among them, 31 cases were diagnosed as multi-primary lung cancer, accounting for 0.67%. Results Among the 31 patients, the incidence of lung cancer in the first and second primary lung cancer was the highest between the 5th and the 6th year, accounting for 64.5 % and 68.2 % respectively. Squamous cell carcinoma accounted for 5 4.7% of the 4 primary cancers. At the same time, cancer, metachronous cancer, and metachronous cancer accounted for 29%, 64.5%, and 6.5%, respectively. X-rays showed that 6 of the 4 primary cancers were more common in peripheral types, accounting for 71.9%. The period is 84.4%. The 5-year survival rate of second-chance cancer secondary cancer was 22.7% (5/22). Conclusions Multiple primary lung cancers are prone to occur in the elderly. The lesions are mostly early, and squamous cell carcinomas are more common. The 5-year survival rate of the second primary cancer is low.