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应用４～５月龄成年鼠和２４月龄以上老年Ｗｉｓｔａｒ大鼠，分别在外科手术显微镜下采用电灼法造成大鼠一侧大脑中动脉闭塞２４ｈ后进行血液稀释治疗２ｈ，检测心肌酶活性。结果表明：脑卒中后心肌损伤程度以老年大鼠为重，经血液稀释治疗后，心肌组织Ｎａ＋－Ｋ＋－ＡＴＰａｓｅ，Ｃａ２＋－ＡＴＰａｓｅ，超氧化物歧化酶（ＳＯＤ），丙二醛（ＭＤＡ）和Ｎ－乙酰－β－Ｄ－氨基葡萄糖苷酶ＮＡＧａｓｅ两个年龄组均有一定程度的变化，以成年组治疗效果优于老年组大鼠，说明血液稀释对闭塞单侧大脑中动脉所致成年、老年大鼠心肌损伤有一定的治疗作用。
The rats aged 4 ~ 5 months and the Wistar rats aged 24 months or older were killed by hemodilution after 24h occlusion of middle cerebral artery occlusion for 24 hours in rats under the operating microscope. The activity of myocardial enzymes was measured. The results showed that the degree of myocardial injury after stroke was the highest in aged rats. After hemodilution, the levels of Na + -K + -ATPase, Ca2 + -ATPase, superoxide dismutase (SOD), malondialdehyde (MDA) N-acetyl-β-D-glucosaminidase NAGase both age groups have a certain degree of change, the treatment effect of adult group is superior to the old group of rats, indicating that hemodilution of occlusion of unilateral middle cerebral artery caused by adult, Aged rats with myocardial injury have a certain therapeutic effect.