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目的 :探讨 L-肉碱 (BT)对肥胖大鼠体重及体质成分变化等的影响。方法 :以高脂饲料诱导大鼠肥胖模型 ,然后将肥胖模型鼠随机分为照组与 12 5 m g/ kg BW、 2 5 0 mg/ kg BW、 5 0 0 mg/ kg BW L-肉碱组 ,每天 1次经口给予 ,共 6周。观察大鼠体重、睾丸 +肾脂肪垫重量的变化。结果 :12 5 mg/ kg BW、 2 5 0 mg/ kg BW与 5 0 0 m g/ kg BW组的动物体重 (BW)低于对照组 (P<0 .0 5 )。结论 :L-肉碱具有减轻大鼠肥胖程度及相对增加瘦体质的作用
Objective: To investigate the effects of L-carnitine (BT) on body weight and body composition of obese rats. Methods: The rat model of obesity was induced by high-fat diet. The model rats were randomly divided into two groups: control group (125 mg / kg BW, 250 mg / kg BW, 500 mg / kg BW L- , Given orally once daily for 6 weeks. Observe the body weight, testicular + kidney fat pad weight changes. Results: The BW of 125 mg / kg BW, 250 mg / kg BW and 500 mg / kg BW group was lower than that of the control group (P <0.05). Conclusion: L-carnitine has the effect of reducing obesity and increasing lean body mass in rats