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目的观察肺炎清直肠浓缩液治疗小儿合胞病毒肺炎的临床疗效并探讨其作用机理。方法将入选病例随机分为西药加肺炎清直肠浓缩液治疗组(治疗组,36例)及单纯西药治疗组(对照组,36例),观察临床疗效及其对患儿免疫功能(IgA、IgG、IgE、CD3、CD4)等指标的影响。结果治疗组36例中治愈28例(77·8%),显效4例(11·1%),有效2例(5·5%),无效2例(5·6%),总有效率94·4%;对照组36例中治愈20例(55·6%),显效7例(19·4%),有效6例(16·7%),无效3例(8·3%),总有效率91·7%。治疗组治愈率明显优于对照组(P<0·05);并能提高血IgA、IgG、CD3、CD4、CD4/CD8,降低血IgE,与对照组比较差异有显著性(P<0·05)。结论肺炎清直肠浓缩液具有治疗小儿合胞病毒肺炎的作用,且未见不良反应,其机理之一可能与调节免疫功能有关。
Objective To observe the clinical effect of pneumonic rectal concentrates on children with syncytial virus pneumonia and to explore its mechanism. Methods The selected cases were randomly divided into three groups: treatment group (36 cases) and medicine group (control group, 36 cases). The clinical efficacy and immunological function (IgA, IgG , IgE, CD3, CD4) and other indicators. Results In the treatment group, 28 cases were cured (77.8%), 4 cases (11.1%) were effective, 2 cases (5.5%) were effective, 2 cases (5.6%) were ineffective and the total effective rate was 94 · In the control group, 20 cases (55.6%) were cured in 36 cases, 7 cases (19.4%) were markedly effective, 6 (16.7%) were effective and 3 (8.3%) were ineffective Effective rate of 91.7%. The cure rate in the treatment group was significantly better than that in the control group (P0.05), and the levels of IgA, IgG, CD3, CD4, CD4 / CD8 and IgE in the blood were significantly increased 05). Conclusions Pneumoconiosis concentrate has the effect of treating children with syncytial virus pneumonia and has no adverse reactions. One of the mechanisms may be related to the regulation of immune function.