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产后哺乳是自然避孕方法之一。哺乳的时间、次数和方法等与闭经时间的长短有密切的因果关系。神经内分泌学研究证明,哺乳性闭经主要是由吸吮刺激产生的。一方面,吸吮刺激高催乳素血症的产生,从而抑制卵泡的发育;另一方面,吸吮显著增加脑内β-内啡肽的释放,β-内啡肽不仅通过抑制多巴胺的释放来产生高催乳素血症,而且,它本身在下丘脑水平可抑制GnRH的合成和释放,使垂体LH分泌减少。因此,催乳素和β-内啡肽均在哺乳性闭经中起主要作用。
Postpartum breastfeeding is one of the natural contraceptive methods. Breastfeeding time, frequency and method of amenorrhea with the length of time has a close causal relationship. Neuroendocrinology studies have shown that lactating amenorrhea is mainly caused by sucking stimuli. On the one hand, sucking stimulates the production of hyperprolactinemia, thereby inhibiting follicular development; on the other hand, sucking significantly increases the release of beta-endorphin in the brain, which is not only produced by inhibiting the release of dopamine Prolactinemia, moreover, it itself inhibits the synthesis and release of GnRH in the hypothalamus and reduces the secretion of pituitary LH. Therefore, both prolactin and beta-endorphin play a major role in mammalian amenorrhea.