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目的分析腹腔镜根治性手术治疗结直肠癌的安全性,并观察其临床疗效。方法 56例结直肠癌患者随机分为对照组和研究组,各28例。对照组患者采用常规开腹手术,研究组实施腹腔镜根治性手术。比较两组患者手术情况(手术时间、术中出血量、淋巴结清扫个数),术后预后情况(排气时间、住院时间、并发症发生率),术后3年后无瘤生存率。结果研究组手术时间为(214.7±108.5)min短于对照组的(322.7±113.7)min;术中出血量为(201.8±110.6)ml少于对照组的(317.8±106.5)ml,差异均具有统计学意义(P<0.05)。研究组与对照组淋巴结清扫个数分别为(10.7±3.6)及(10.3±3.5)个,两组比较差异无统计学意义(P>0.05)。研究组排气时间为(28.5±4.6)h少于对照组(37.0±5.3)h,住院时间为(9.3±3.5)d少于对照组的(14.2±3.4)d,术后并发症发生率为14.29%低于对照组的39.29%,差异均具有统计学意义(P<0.05)。随访3年后,研究组与对照组无瘤生存率分别为64.29%及60.71%,比较差异无统计学意义(P>0.05)。结论腹腔镜根治性手术治疗结直肠癌的手术创伤小,术后并发症较少,安全性较好,值得推广应用。
Objective To analyze the safety of laparoscopic radical surgery for colorectal cancer and observe its clinical efficacy. Methods 56 patients with colorectal cancer were randomly divided into control group and study group, 28 cases in each. The control group patients underwent conventional laparotomy, and the study group underwent laparoscopic radical surgery. The operation conditions (operation time, intraoperative blood loss, number of lymph node dissection), postoperative prognosis (exhaust time, hospitalization time, complication rate) were compared between two groups. The tumor-free survival rate was 3 years after operation. Results The operative time of the study group was (214.7 ± 108.5) min which was shorter than that of the control group (322.7 ± 113.7) min. The blood loss during the operation was (201.8 ± 110.6) ml less than that of the control group (317.8 ± 106.5) ml, Statistical significance (P <0.05). The numbers of lymph node dissection in study group and control group were (10.7 ± 3.6) and (10.3 ± 3.5), respectively. There was no significant difference between the two groups (P> 0.05). The exhaust time of the study group was (28.5 ± 4.6) h less than that of the control group (37.0 ± 5.3) h, and the duration of hospitalization was (9.3 ± 3.5) days less than that of the control group (14.2 ± 3.4) days. The postoperative complication rate 14.29% lower than 39.29% of the control group, the differences were statistically significant (P <0.05). After 3 years of follow-up, the tumor-free survival rates of study group and control group were 64.29% and 60.71% respectively, with no significant difference (P> 0.05). Conclusions Laparoscopic radical surgery for colorectal cancer is less traumatic and less postoperative complications, safety is good, it is worth popularizing and applying.