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对30例肺心病尸检病例的肝脏形态学变化进行系统的观察,其病理改变表现为肝瘀血、脂肪变性、肝板解离和肝细胞坏死。4例死前有长达7 d 以上的持续性低氧血症的病例,肝脏发生了小叶中心性大片状肝细胞凝固性坏死,此病变与生前肝功能变化进行了对照分析。作者还发现肺心病病人心衰时间过长可发生肝硬化,其特点是:心衰史多在10 a 以上;肝硬化的形态特征是反常小叶形成。肺心病人虽也能发生肝硬化,但明显地低于其他类型的心脏病。
The morphological changes of the liver in 30 cases of autopsy of cor pulmonale were systematically observed. The pathological changes were liver cirrhosis, steatosis, hepatic plate dissociation and hepatocyte necrosis. 4 cases of persistent hypoxemia for up to 7 days before death, coagulation necrosis of large lobule hepatocellular lobe in the liver occurred, and the changes of this lesion were compared with the changes of liver function in prenatal period. The authors also found that chronic heart failure in patients with pulmonary heart disease can occur cirrhosis of the liver, characterized by: heart failure more than 10 a; liver cirrhosis is characterized by abnormal lobular formation. Although pulmonary heart disease can occur in patients with cirrhosis, but significantly lower than other types of heart disease.