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何杰金病脊髓内转移罕见,临床表现常无特异性,诊断困难。一旦出现神经系统症状,则预后不良。作者报告1例32岁女患者,主诉左下肢麻木伴刺痛,且逐渐累及左半身。近一周右足下垂及右手无力。查体见右霍纳氏综合征,右侧肢体肌力差,右侧深腱反射亢进,右巴彬斯基征(+)。右锁骨上可触及2cm之淋巴结,活检示结节硬化性何杰金病。胸片示纵膈肿块,脊髓造影示C_6-C_7脊髓段梭形增宽,CT扫描示C_6-C_7髓内肿瘤向髓外延伸,核磁共振扫描在T_1加权图象上示C_6-C_7脊髓膨出。脑脊液,淋巴管造影,骨扫描及骨髓活检等均正常。确诊后即用地塞米松及包
Hodgkin’s disease rare spinal cord metastasis, often non-specific clinical manifestations, diagnosis difficult. In the event of neurological symptoms, the prognosis is poor. The authors report a 32-year-old woman who complained of numbness associated with left lower limb pain and gradually involving the left half of her body. Right foot drooping and right hand weakness in the past week. Check the right to see Horner’s syndrome, right limb muscle weakness, the right side of the tendon hyperreflexia, right Babinski sign (+). Right clavicle can reach 2cm of lymph nodes, biopsy showed tuberous sclerosis Hodgkin’s disease. The chest radiograph showed the mediastinal mass. The myelography of C_6-C_7 spinal cord was broadened in CT scan. The C_6-C_7 intramedullary tumor extended extramedullaryly. The MRI scan showed C_6-C_7 spinal cord bulge . Cerebrospinal fluid, lymphangiography, bone scan and bone marrow biopsy were normal. Dexamethasone and package after diagnosis