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目的 探讨聚乙烯醇 (PVA)子宫动脉栓塞 (UAE)治疗子宫肌瘤的临床疗效及血流动力学的变化。方法 对21例子宫肌瘤患者采用PVA进行UAE治疗 ,并采用脉冲多普勒对术前及术后1、3、6、9、12、18个月子宫动脉平均血流速度 (Vm)、血流量 (BFV)、搏动指数 (PI)和阻力指数 (RI)进行测定。结果 Vm、BFV术后各时点较术前均有显著下降 (均P<0.01) ;PI、RI术后1、3、6个月较术前显著下降 (P<0.01) ,而术后12、18个月恢复了术前水平 (P>0.05)。术后经B超复查瘤体较术前缩小38.88%～100%。结论 使用PVA行UAE后子宫血流动力学经过少血期和恢复期变化 ,于术后12～18个月基本恢复术前水平。血流动力学的这一变化对患者的生育功能无明显影响 ,但适宜受孕时间应在术后12个月以后。肌瘤体积的改变与血流动力学改变相关
Objective To investigate the clinical efficacy and hemodynamic changes of uterine fibroids treated by polyvinyl alcohol (PVA) uterine artery embolization (UAE). Methods Twenty - one patients with uterine fibroids were treated with UAE by UAE. The pulse wave Doppler was used to evaluate the changes of mean uterine artery velocity (Vm), blood BFV, PI and RI were measured. Results The Vm and BFV decreased significantly at all time points after operation (all P <0.01). The PI and RI decreased significantly at 1, 3, and 6 months after operation (P <0.01) , 18 months to restore the preoperative level (P> 0.05). Postoperative B ultrasound examination of the tumor reduced 38.88% ~ 100% compared with preoperative. Conclusions The uterine hemodynamics changes after UAE using PVA in the period of less blood circulation and convalescent period, and basically resume the preoperative level at 12 to 18 months after operation. This change in hemodynamics had no significant effect on the reproductive function of the patient, but the appropriate time for conception should be 12 months after surgery. Changes in fibroid volume correlate with hemodynamic changes