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晚期血吸虫病的特征是门脉区周围纤维化和门静脉肝内分枝阻塞,引起窦前高压。以往对晚期血吸虫病人的血液动力学研究显示门脉高压伴有正常的窦状隙压力。近来研究不同的病例的结果表明,肝硬变时窦状隙压力可以很高,窦性高压的发病机理尚不淡楚。虽少数斑块区可见到肝实质细胞结节状再生,但结合血液动力学和组织学的研究,未能证明其和窦压升高有明显联系。最近已证明在血吸虫病性管状肝纤维化病例中,肝内动脉分枝显著肥大,提示可能与引起窦性高压有关。作者为了进一步研究窦性高压的发病原理,选择了5例肝脾型血吸虫病伴窦性高压的病例和1例对照,研究于控阻肝动脉主干前、当时和以后的嵌入性肝静脉压,即窦状
Advanced schistosomiasis is characterized by fibrosis around the portal area and hepatic portal vein occlusion, causing sinusoidal anomalies. Hemodynamic studies of patients with advanced schistosomiasis have shown that portal hypertension is accompanied by normal sinusoidal pressure. Recent studies of different cases of the results show that cirrhosis sinusoidal pressure can be high, the pathogenesis of sinus hypertension is not yet clear. Although a small number of plaque area can be seen nodular liver cell regeneration, but combined with hemodynamic and histological studies, failed to prove that it was significantly linked with increased sinus pressure. Recently it has been demonstrated that in patients with schistosomiasis-induced tubular fibrosis, intrahepatic arterial branches significantly hypertrophy, suggesting that may cause sinus hypertension. In order to further study the pathogenesis of sinus hypertension, we selected 5 cases of hepatosplenic schistosomiasis with sinus hypertension and 1 case of control, study in the control of the main artery of the hepatic artery, then and after the embedded hepatic venous pressure, That sinusoid