Discovery of the strong antioxidant selenoneine in tuna and selenium redox metabolism

• 作 者: Yumiko Yamashita Takeshi Yabu
• 机 构: NationalResearchInstituteofFisheriesScience,DepartmentofVeterinaryMedicine
• 出 处: 世界生物化学杂志：英文版（电子版）
• 发表日期: 2010年5期
• 关键词: Selenium-containing compound ANTIOXIDANT METHYLMERCURY Organic cations/carnitine
• 基金项目: Supported by In part grants from the Ministry of Agriculture,Forestry,and Fisheries of Japan(Rural Biomass Research Project,BM-D2300)and Fisheries Research Agency

A novel selenium-containing compound,selenoneine,has been isolated as the major form of organic selenium in the blood and tissues of tuna.Selenoneine harbors a selenium atom in the imidazole ring,2-selenylNα,Nα,Nα-trimethyl-L-histidine,and is a selenium a