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目的 探讨静脉注射纤维蛋白原制剂在新生儿弥漫性血管内出血（ＤＩＣ） 治疗中的作用。 方法 ５７ 例新生儿ＤＩＣ病人随机分为治疗组、对照组，静滴纤维蛋白原６ 小时后观察临床表现及凝血指标。 结果 比较治疗组与对照组凝血指标，治疗组６ 小时内止血效果优于对照组（ Ｐ＜ ０ ．０５） ；治疗组与对照组ＤＩＣ抢救成功率比较，治疗组明显高于对照组（ Ｐ＜ ０ ．０５） 。 结论 静脉注射纤维蛋白原制剂在新生儿ＤＩＣ 出血期的治疗中能加快止血，对抗纤溶，提高抢救成功率。
Objective To investigate the role of intravenous fibrinolytic agents in the treatment of neonatal diffuse intravascular hemorrhage (DIC). Methods 57 neonates with DIC were randomly divided into treatment group, control group and intravenous infusion of fibrinogen for 6 hours. The clinical manifestations and coagulation indexes were observed. Results Compared with the control group, the hemostatic effect of the treatment group was better than that of the control group (P <0. 05). The success rate of DIC in the treatment group and control group was significantly higher than that in the control group (P < 0 .05). Conclusion Intravenous fibrinogen preparation can accelerate hemostasis, prevent fibrinolysis and improve the success rate of rescue in the treatment of neonatal DIC hemorrhage.