Simultaneous determination of 12, 13-dihydroxyeuparin and glycyrrhizic acid in Yanyanfang mixture by

• 作 者: Zhi-Sheng Xie Xin-Jun Xu Chun-
• 机 构: SchoolofPharmaceuticalSciences,TheFirstAffiliatedHospital
• 出 处: 药物分析学报：英文版
• 发表日期: 2011年3期
• 关键词: 反相高效液相色谱法 同时测定 甘草酸 混合物 HPLC 梯度洗脱 线性关系 浓度范围 12 13-Dihydroxy-euparinGlycyrrhizic
• 基金项目: Acknowledgments This work was supported by Guangdong Natural Product Reference Material Research ＆ Development Central Lab, the First Affiliate Hospital of Sun Yat-sen University and the Industry-Univ

A reversed phase high performance liquid chromatography (HPLC) method was established for the simultaneous determination of 12,13-dihydroxyeuparin and glycyrrhizic acid in Yanyanfang mixture.A Grace Apollo C 18 column (250 mm 4.6 mm,5 mm) was used as the