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目的：观察雷尼替丁治疗复发性口腔溃疡的疗效。方法：治疗组６０例（男性３１例，女性２９例；年龄２４±ｓ７ａ），用雷尼替丁０．１５ｇ，ｐｏ，ｂｉｄ及局部涂抹纯雷尼替丁药粉，ｔｉｄ；对照组６０例（男性３３例，女性２７例；年龄２３±９ａ），用甲硝唑０．４ｇ和维生素Ｂ２１０ｍｇ，ｐｏ，ｔｉｄ及局部贴粘０．０２％氯己定口腔溃疡膜，ｔｉｄ。结果：用药后的总有效率治疗组和对照组分别为１００％和８５％，２组间差异非常显著（Ｐ＜０．０１）。结论：雷尼替丁治疗复发性口腔溃疡见效快，疗程短，无不良反应，复发周期延长，复发率低。
Objective: To observe the efficacy of ranitidine in the treatment of recurrent oral ulcer. Methods: The treatment group of 60 patients (31 males and 29 females; age 24 ± s7a), with ranitidine 0.15g, po, bid and topical application of pure ranitidine powder, tid; control group of 60 patients ( Male 33 cases, female 27 cases; age 23 ± 9a), with metronidazole 0.4g and vitamin B210mg, po, tid and local sticky 0.02% chlorhexidine oral ulcer membrane, tid. Results: The total effective rate after treatment was 100% in the treatment group and 85% in the control group, with significant difference between the two groups (P <0.01). Conclusions: Ranitidine is effective in treating recurrent oral ulcer with short course of treatment, no adverse reaction, prolonged recurrent period and low recurrence rate.