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探讨难治性肾病综合征患儿载脂蛋白（Apo）五基因多态性的变化及其对血浆脂类的影响，了解ApoE基因在难治性肾病发生发展中的意义。一、材料与方法1．对象及标本来源：病例均为对激素耐药、经常复发或激素依赖的难治性肾病综合征患儿，共计46例，男41例，女5例，年龄25－13岁，
To investigate the changes of apolipoprotein (Apo) five gene polymorphism and its effect on plasma lipids in children with refractory nephrotic syndrome and to understand the significance of ApoE gene in the development of refractory nephropathy. First, materials and methods 1. Subjects and specimens Source: The cases were hormone-resistant, recurrent or hormone-refractory nephrotic syndrome in children, a total of 46 cases, 41 males and 5 females, aged 25-13 years old,