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目的 :观察骛马四磨汤口服液对小鼠胃肠运动的影响 ,并与胃肠道促动力剂莫沙比利进行比较。方法 :以胃肠内标记物葡聚糖蓝 -2 0 0 0在胃内色素相对残留量及小肠推进比为指标 ,观察各实验组对正常小鼠胃排空及肠推进的影响。结果 :骛马四磨汤口服液对正常小鼠的胃排空及肠推进运动均起到明显的促进作用 ,但其促胃排空作用较莫沙比利弱 ,而对肠推进运动的促进作用与莫沙比利相比则无显著性差异。结论 :骛马四磨汤口服液具有加快胃排空及促进肠蠕动作用
Objective : To observe the effect of Gengma Simotang oral liquid on gastrointestinal motility in mice and compare it with Mosapride, a gastrointestinal motility agent. METHODS: The effects of each experimental group on gastric emptying and intestinal propulsion in normal mice were observed with intragastric pigment relative residuals and small intestine advancing ratio as indicators of the intragastric marker dextran blue -200. Results: Gengma Simotang Oral Liquid played an important role in promoting gastric emptying and intestinal propulsion in normal mice, but its gastric emptying effect was weaker than that of mosapride, but it promoted intestinal propulsion. The effect was not significantly different from that of mosapride. Conclusion : Gengma Simotang Oral Liquid can accelerate gastric emptying and promote intestinal peristalsis