Breviscapine attenuates acute pancreatitis by inhibiting expression of PKCα and NF-κB in pancreas

• 作 者: Hong Zhang Cui-Zhu Cai Xiao-Qi
• 机 构: DepartmentofPathophysiology,DepartmentofInternalMedicine
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2011年14期
• 关键词: 急性胰腺炎 蛋白激酶C 灯盏花素 衰减 WESTERN印迹 急性坏死性胰腺炎 血清淀粉酶 ANP Breviscapine Acute pancreatiti
• 基金项目: Supported by Funds of Natural Science of Shaanxi Education No.05JK176, Natural Science of Shaanxi Province No.2010JM4023, Natural Science of Xianyang City No. 2010K14-02（6）

AIM:To study the effect of breviscapine (Bre) on activity of protein kinase Cα (PKCα) and nuclear factor (NF)-κB in pancreas,and the mechanism of Bre attenuating acute pancreatitis (AP). METHODS:One hundred and eight rats were randomly divided into acute