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目的:探讨闭合性胸部外伤合并心肌损伤患者心肌标志物变化规律。方法:选取在我院进行治疗的42例闭合性胸部外伤合并心肌损伤的患者为研究对象,将其设为观察组,同时选取42例单纯损伤未伴心肌损伤的患者为对照组,分别检测对照组及观察组伤后1h、12h、24h及48h血清肌钙蛋白I、C反应蛋白、B型尿钠肽、肌红蛋白的水平,并将结果加以总结及比较。结果:经研究比较发现,观察组血清肌钙蛋白I、肌红蛋白、B型尿钠肽、C反应蛋白随着时间的推移均呈现上升趋势,血清肌钙蛋白I、肌红蛋白、B型尿钠肽24h达峰值,血清C反应蛋白则于12h左右达到高值,且均高于对照组(P<0.05或P<0.01),有显著性差异或非常显著性差异。结论:胸部外伤合并心肌损伤患者受伤后1h、12h、24h及48h血清肌钙蛋白I、C反应蛋白、B型尿钠肽、肌红蛋白的水平的变化有着一定的规律,在其诊断及治疗中有一定的作用。
Objective: To investigate the changes of myocardial markers in patients with closed chest trauma combined with myocardial injury. Methods: Forty-two patients with closed chest injury and myocardial injury treated in our hospital were selected as the study group, and 42 patients with simple injury without myocardial injury were selected as the control group. The levels of serum troponin I, C-reactive protein, B-type natriuretic peptide and myoglobin at 1h, 12h, 24h and 48h after injury were observed and compared. Results: The study found that serum levels of troponin I, myoglobin, B-type natriuretic peptide and C-reactive protein in the observation group showed an upward trend over time, serum troponin I, myoglobin, type B The peak of urinary natriuretic peptide reached the peak value at 24h and the serum C-reactive protein reached a high value at about 12h, both of which were significantly higher than those of the control group (P <0.05 or P <0.01). There was a significant difference or a very significant difference. Conclusion: The changes of serum troponin I, C-reactive protein, B-type natriuretic peptide and myoglobin in patients with chest trauma complicated with myocardial injury at 1h, 12h, 24h and 48h after injury have certain rules. In the diagnosis and treatment In a certain role.