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肝吸虫病是一种重要的人兽共患寄生虫病,也是我国重点防治主要食源性寄生虫病之一。肝吸虫感染被国际癌症研究中心(IARC)确定为Ⅰ类致癌因素,其所致胆管癌是肝吸虫感染的严重后果之一。本文就目前国内外肝吸虫感染的流行病学及其诱发胆管癌的发病机制研究进展和成果做一综述,为今后学者进一步深入研究肝吸虫病提供参考资料。
Hydatidiasis is an important zoonotic parasitic disease, but also one of the major foodborne parasitic diseases in our country. Hepatic infection is identified by the International Agency for Research on Cancer (IARC) as a class I carcinogen, and cholangiocarcinoma is one of the serious consequences of hepatic fluke infection. This review summarizes the current research progress and achievements of the epidemiology of hepatic fluke inoculation and its pathogenesis of inducing cholangiocarcinoma at home and abroad, and provides references for further study of hepaticosis.