Lipopolysaccharide ＂Two-hit＂ Induced Refractory Hypoxemia Acute Respiratory Distress Model in Rats

• 作 者: 李玉梅 卫洪昌
• 机 构: DepartmentofPathology
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2009年4期
• 关键词: 内毒素 模型 呼吸 急性 大鼠 诱发 低氧 acute respiratory distress syndrome （ARDS） acute lung inj

To establish a stable and reliable model of refractory hypoxemia acute respiratory distress syndrome(ARDS)and examine its pathological mechanisms,a total of 144 healthy male Wistar rats were randomized into 4 groups:groupⅠ(saline control group),groupⅡ(LPS