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目的探讨甲硝唑缓释药膜治疗牙周炎的临床疗效。方法将我院在2010年3月到2012年12月期间收治的140例牙周炎患者随机分为治疗组和对照组,治疗组患者给予甲硝唑缓释药膜进行治疗,对照组患者给予碘甘油进行治疗。结果治疗组患者的显效率和好转率明显比对照组高,存在的差异性具有统计学意义(P<0.05);治疗组患者牙龈出血的指数和牙周袋的深度明显低于对照组患者,存在的差异性具有统计学意义(P<0.05)。结论甲硝唑缓释药膜应用于治疗牙周炎取得的临床疗效显著,降低了不良反应的发生率,值得在临床上广泛使用和推广。
Objective To study the clinical effect of metronidazole sustained-release film on periodontitis. Methods A total of 140 patients with periodontitis treated in our hospital from March 2010 to December 2012 were randomly divided into treatment group and control group. Patients in the treatment group were given metronidazole sustained-release membrane for treatment. Patients in the control group were given Iodine glycerol for treatment. Results The effective rate and improvement rate of the treatment group were significantly higher than those of the control group (P <0.05). The index of gingival bleeding and the depth of the periodontal pocket in the treatment group were significantly lower than those in the control group The existence of the difference was statistically significant (P <0.05). Conclusion Metronidazole sustained-release membrane for the treatment of periodontitis achieved significant clinical efficacy, reducing the incidence of adverse reactions, it is widely used in clinical and promotion.