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目的 研究疟史对健康人和发热病人原虫血症的作用。 方法 1989年 5月和 10月在中国云南省沧源县班老乡作了两次横断面调查。专业人员在对健康人采血、涂片、镜检的同时 ,进行问卷调查 ,调查内容包括疟史、性别、居住地海拔及村名 5个方面。在 4月和 10月期间收集发热病人的情况 ,用 EPI INFO 6 .0和 STATA 5 .0软件对数据进行处理。 结果 单因素分析发现疟史和年龄是无症状带虫者 [ML H比值比为 3.98(95 %可信限为 2 .48～ 6 .40 ) ,年龄 2 1～ 40的比值比为 0 .19(95 %可信限为 0 .0 9～0 .39) ,年龄≥ 40的比值比为 0 .38(95 %可信限为 0 .16～ 0 .90 ) ]的危险因素。多因素分析发现年龄是混杂因素 ,冲淡了疟史的作用 ;而疟史是原虫血症发热病人的保护因素 [比值比为 0 .37(95 %可信限为 0 .2 1～ 0 .6 5 ) ]。 结论 有疟史者很有可能是无症状的带虫者 ,是传播疟疾的传染源 ,应在早期阶段就对其重新治疗。疟史对健康人再次感染疟疾有抑制作用
Objective To study the effect of malaria history on protozoalosis in healthy and febrile patients. Methods Two cross-sectional surveys were conducted in Ban Lao, Cangyuan County, Yunnan Province, China in May and October 1989. Professionals in the blood of healthy people, smear, microscopic examination at the same time, the survey, the survey includes malaria history, gender, residential area elevation and village name 5 aspects. Fever patients were collected during April and October and were processed using EPI INFO 6.0 and STATA 5.0 software. Results Univariate analysis showed that the history of malaria and the age of asymptomatic insects [ML H odds ratio 3.98 (95% confidence interval 2.48 ~ 6.40), the ratio of age 21 to 40 was 0.19 (95% CI 0.90 to 0.39), odds ratio 0.38 (95% confidence interval 0.16-0.90) for age ≥40]. Multivariate analysis found that age is a confounding factor, diluting the role of malaria history; malaria history is a protective factor in patients with fever caused by parasitemia [odds ratio was 0.37 (95% confidence interval was 0.21 ~ 0.6 5)]. Conclusion Most people who have a history of malaria are asymptomatic carriers of the disease and are sources of transmission of malaria and should be re-treated at an early stage. Malaria history of healthy people once again infected with malaria inhibitory effect