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作者在1965年12月至1972年3月观察了接受肾脏移植的患者35例,长期应用大量免疫抑制剂后所发生的皮肤并发症。免疫抑制剂的用量情况为:在即将接受肾脏移植手术前静脉输入含有氢化可的松500毫克及环磷酰胺200毫克的葡萄糖溶液。术后第一周每天给以500毫克氢化可的松,之后,再逐渐减量并改为口服强的松,其每日用量递减至第三个月末时为30毫克,进一步减量以后再考虑。另外在尿闭期间每天给以
From December 1965 to March 1972, the authors observed 35 patients who underwent kidney transplantation and the skin complications that occurred after chronic immunosuppressive agents were used for a long time. The amount of immunosuppressant used was: intravenous infusion of 500 mg of hydrocortisone and 200 mg of cyclophosphamide in a glucose solution immediately prior to renal transplant surgery. After the first week of giving 500 mg of hydrocortisone daily, then gradually tapering and changed to oral prednisone, the daily dosage decreased to 30 mg at the end of the third month, after further reduction and then consider . In addition, during the urine to give every day