论文部分内容阅读
目的探讨羟苯磺酸钙联合依那普利治疗糖尿病肾病蛋白尿的疗效。方法将本院收治的54例糖尿病肾病患者随机分为对照组和观察组,两组均给予依那普利治疗,仅观察组加用羟苯磺酸钙;分析两组的治疗效果及治疗前、治疗8周后的尿α1-微球蛋白(α1-MG)、微量白蛋白(mAlb)及尿蛋白的水平。结果观察组的总有效率高于对照组(88.89%vs 66.67%,P<0.05);两组治疗的α1-MG、mAlb和24h尿蛋白均低于治疗前;治疗组治疗后的3指标均低于对照组,以上均有统计学差异。结论羟苯磺酸钙联合依那普利治疗糖尿病肾病蛋白尿的效果较好,不仅提高治疗有效率,而且还可降低蛋白尿相关指标。
Objective To investigate the efficacy of calcium dobesilate and enalapril in the treatment of diabetic nephropathy proteinuria. Methods 54 cases of diabetic nephropathy admitted to our hospital were randomly divided into control group and observation group. Enalapril was given to both groups, only the observation group was given calcium dobesilate. The therapeutic effect of the two groups was compared before treatment Urinary α1-microglobulin (α1-MG), microalbumin (mAlb) and urinary protein levels after 8 weeks of treatment. Results The total effective rate in the observation group was higher than that in the control group (88.89% vs 66.67%, P <0.05). The α1-MG, mAlb and 24-hour urinary protein in the two groups were lower than before treatment Lower than the control group, the above are statistically significant. Conclusion Calcium dobesilate and enalapril treatment of diabetic nephropathy proteinuria better, not only improve the treatment efficiency, but also reduce proteinuria related indicators.