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本文测定了36例脑膜炎患者血清、红细胞膜及脑脊液唾液酸(SA)含量。结果,化脑及结脑血清、脑脊液SA明显高于对照组,红细胞膜SA明显低于对照组;病脑患者血清、红细胞膜及脑脊液SA含量与对照组无显著差异;不同性别、年龄组间血清、红细胞膜及脑脊液SA含量亦无显著性差异。提示脑膜炎患者血清、红细胞膜及脑脊液SA含量变化可以反映其脑损伤的程度,对指导治疗、判定预后具有一定的参考意义。
In this paper, 36 cases of meningitis patients serum, erythrocyte membrane and cerebrospinal fluid sialic acid (SA) content. The results showed that the levels of SA in cerebrospinal fluid and cerebrospinal fluid were significantly higher than those in the control group, and the SA of erythrocytes was significantly lower than that in the control group. There was no significant difference in the content of SA in the serum, erythrocyte membrane and cerebrospinal fluid between the patients with cerebrovascular disease and the control group. Serum, erythrocyte membrane and cerebrospinal fluid SA content was no significant difference. These results suggest that the changes of SA content in serum, erythrocyte membrane and cerebrospinal fluid of patients with meningitis can reflect the degree of brain injury, which is of certain reference value for guiding treatment and prognosis.