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目的：探讨1983～1994年间高原地区中老年患者GC及PD临床流行病学特点。方法：回顾性统计分析居住在海拔2260～4500：高度之间的入我院老年病房12年间副处级以上干部、工程师、教师、医师等6262例中GC及PD入院率、病死率变迁情况，并对本组患者的年龄、性别、居住情况及血型等多元因素进行综合性研究。结果：青海地区中老年人GC平均入院率1．64％，病死率0．75％；平均PD入院率4．29％。GC及PD前6年病死率、入院率均大于后6年，趋势检验P（1）＜0．025。年龄分布GC以65～74岁为死亡高峰（1．20％），85岁以后病死率为零。GC死亡占肿瘤死亡的首位。GC入院率、病死率世居者大于移居者，PD入院率世居者小于移居者，统计学处理无差异P＜0．05。GC组血型构成比以A型为主59．17％，而其肿瘤组以B型为主37．14％。PD入院率、病死率呈下降趋势。GC的病死率随年龄增长而增高，发病年龄偏轻，患者寿命明显缩短。推测世居者GC入院率、病死率高，患病年龄偏轻与卫生条件差、低氧、饮食习惯不良有关。GC显示与A型血密切相关，PD与O型血有关。因此，高原地区该病与遗传的关系，有待进一步研究。
Objective: To investigate the clinical epidemiological characteristics of GC and PD in middle-aged and elderly patients from 1983 to 1994. Methods: We retrospectively analyzed the changes in GC and PD admission rates and mortality rates among the 6262 cadres, engineers, teachers, and doctors who had lived in the elderly wards at the altitude of 2260-4500: altitude for 12 years. A comprehensive study was conducted on multiple factors such as age, sex, living conditions, and blood type of this group of patients. Results: The average GC admission rate in middle-aged and elderly people in Qinghai was 1.64%, the mortality rate was 0.75%, and the average PD admission rate was 4.29%. The 6-year mortality rate and admission rate of GC and PD were greater than that of the next 6 years. The trend test was P(1)<0.025. The age distribution of GC was 65-74 years old as the death peak (1.20%), and the mortality rate after the age of 85 was zero. GC death accounted for the first death of cancer. GC admissions and mortality rates were higher for those in the household than those who migrated, and those with a PD admission rate were smaller than those for immigrants. Statistically, there was no difference (P<0.05). In the GC group, the proportion of the blood group was 59.17% in the A type, and the B type in the tumor group was 37.14%. PD admission rate and mortality rate showed a downward trend. The mortality rate of GC increased with age, the age of onset was lighter, and the life expectancy of patients was significantly shortened. It is estimated that the GC’s hospital admission rate and mortality rate are high, and the younger age of illness is related to poor sanitation, hypoxia, and poor eating habits. GC shows a close relationship with type A blood and PD is associated with type O blood. Therefore, the relationship between the disease and heredity in highland areas needs further study.