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β-阻滞剂通常对改善心绞痛患者的运动耐量有效,但此种改善常仅呈部分性。二硝基异山梨醇酯(ISDN),硝苯吡啶,异搏停均为加强心得安抗心绞痛效用的补充药物。本文旨在比较应用最佳剂量心得安而仍有心绞痛的患者,加用上述三种血管扩张剂的相对抗心绞痛效果。方法:10例典型劳累型心绞痛男性患者,均无高血压或充血性心力衰竭。患者先经多次踏车试验求出能在运动3～6分钟间激发心绞痛的起始运动水平。心得安治疗的剂量是不再能增加疗效的最大剂量,平均为每日218毫克。试验分4天进行,患者于清晨服心得安,休息30分钟后作踏车运动试验直
Beta-blockers are usually effective in improving exercise tolerance in patients with angina, but this improvement is often only partial. Isosorbide dinitrate (ISDN), nifedipine, verapamil are added to enhance the efficacy of anti-angina pectoris supplements. The purpose of this article is to compare the relative anti-anginal effects of the above three vasodilators in patients who have the best dose of prophylaxis but who still have angina. Methods: Ten patients with typical exertional angina were not hypertensive or congestive heart failure. Patients first treadmill test to find out in 3 to 6 minutes of exercise to stimulate angina starting exercise level. Andean treatment dose is no longer able to increase the maximum dose of the effect, an average of 218 mg daily. The test was carried out in 4 days. The patient was comfortable in the early morning and was tested for treadmill exercise after resting for 30 minutes