论文部分内容阅读
目的了解围产期孕妇B群链球菌(GBS)的带菌及耐药情况,为临床用药提供依据。方法对2015年10月至2016年1月来龙岩市人民医院产前检查孕35~37周的妇女1 143名,采集直肠拭子和阴道拭子培养分离GBS,对分离出GBS进行药物敏感试验。结果1 143名孕妇中GBS检出率7.6%(87/1 143),直肠拭子检出率6.2%(71/1 143),阴道拭子检出率4.3%(49/1 143),直肠和阴道拭子同时检出33例(2.9%)。药敏试验结果:对青霉素、氨苄西林和万古霉素100.0%敏感,后依序为左氧氟沙星65.9%敏感、克林霉素53.7%、红霉素50.0%、四环素7.3%。结论孕产妇B群链球菌感染较高,临床应积极开展GBS常规检测,同时送检直肠拭子和阴道拭子可提高GBS检出率。
Objective To understand the carrier and drug resistance of Streptococcus group B Streptococcus (GBS) in pregnant women during perinatal period, and to provide basis for clinical medication. Methods A total of 1 143 women aged 35-37 weeks before antenatal examination in Longyan People’s Hospital from October 2015 to January 2016 were enrolled in this study. Rectal swabs and vaginal swabs were collected and cultured to isolate GBS. GBS was isolated for drug susceptibility testing . Results The detection rate of GBS in 1 143 pregnant women was 7.6% (87/1 143), rectal swab was 6.2% (71/1 143), vaginal swab was detected in 4.3% (49/1 143) And vaginal swab at the same time detected in 33 cases (2.9%). Drug susceptibility test results: sensitive to 100.0% of penicillin, ampicillin and vancomycin, sensitive to 65.9% levofloxacin, clindamycin 53.7%, erythromycin 50.0%, tetracycline 7.3%. Conclusion The group B streptococcal infection in pregnant women is higher. The clinical practice of GBS should be carried out routinely. At the same time, rectal swab and vaginal swab should be taken to improve the detection rate of GBS.