来曲唑致心律失常

• 作 者: 章必成 高建飞 杜光祖 李欣
• 机 构: 广州军区武汉总医院,广州军区武汉总医院,广州军区武汉总医院,广州军区武汉总医院 湖北武汉430070,湖北武汉430070,湖北武汉430070,湖北武汉430070
• 出 处: 药物不良反应杂志
• 发表日期: 2004年03期
• 关键词: 来曲唑 乳腺癌根治术 浸润性导管癌 孕激素受体 雌激素受体 肿块大小 术后病理 患者 腋窝下 淋巴结 转移 呕吐 恶心

Summary A 41-year-old woman experienced breast cancer removed by surgery with chemotherapy and radiotherapy. 15 days after taking letrozole 2.5mg daily by mouth, the patient felt flustered and the heart rate was 100-110 beats/min. Heart examination by color ultrasound showed normality while ECG showed atrial premature beat, 6-20 beats/min. The patient’s heart rate and ECG recovered gradually after a stop of medication.7 days later,taking another letrozole caused the above symptoms again.The symptoms resolved after discontinuation of letrozole.

Summary A 41-year-old woman experienced breast cancer removed by surgery with chemotherapy and radiotherapy. 15 days after taking letrozole 2.5mg daily by mouth, the patient felt flustered and the heart rate was 100-110 beats / min. Heart examination by color ultrasound showed normality while ECG showed atrial premature beat, 6-20 beats / min. The patient’s heart rate and ECG recovered gradually after a stop of medication.77 days later, taking another letrozole caused the above symptoms again. These symptoms resolved after discontinuation of letrozole.