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血液透析患者使用中心静脉留置导管后易出现如感染、生物膜形成、系统抗凝风险和导管功能不良等并发症。封管液的目的是为了抗凝和减少导管内血栓形成,同时还具有防止感染和减少导管生物膜形成的作用。临床上常用的封管液有普通肝素、低分子肝素以及枸橼酸盐等。解放军总医院第一附属医院肾内科李冀军教授撰写的中心静脉导管封管液研究进展总结了肝素封管液的特点,探讨高浓度肝素增加血透患者肝素出血风险的原因,综述近年导管
Hemodialysis patients prone to complications such as infection, biofilm formation, systemic anticoagulant risk, and poor catheterization after catheterization with a central venous catheter. The purpose of sealing tube solution is to anticoagulant and reduce intraductal thrombosis, but also to prevent infection and reduce the role of catheter biofilm formation. Commonly used in clinical seal fluid are unfractionated heparin, low molecular weight heparin and citrate. The First Affiliated Hospital of PLA General Hospital, Department of Nephrology, Professor Li Jijun written by the central venous catheter sealing tube Research Progress Summary of the characteristics of heparin sealed tube fluid, to explore the high concentration of heparin hemodialysis patients to increase the risk of heparin bleeding, review of recent years, catheter