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本文以小鼠为实验材料，预先给低水平电离辐射，３—６ｈ再次接受大剂量Ｘ线全射照射，观察低剂量辐射对大剂量诱变作用的拮抗作用。实验结果证明：以染色体畸变为观测终点，则骨髓细胞和初级精母细胞染色体畸变均低于单纯大剂量组（Ｐ＜０．０１）。雄鼠预先经０．０５ＧｙＸ线处理６ｈ后照射２．０ＧｙＸ线，在９ｗｋ内的受育率明显高于单纯大剂量照射组（Ｐ＜０．０１）。说明低水平电离辐射不仅具有降低小鼠遗传物质的损伤作用，而且可以提高受大剂量照射小鼠的生育能力。
In this paper, mice were used as experimental materials, low-level ionizing radiation was preliminarily administered, and high-dose X-ray full irradiation was again conducted 3-6 hours later to observe the antagonistic effect of low dose radiation on large dose mutagenesis. Experimental results show that: chromosome aberration as the end point of observation, the bone marrow cells and primary spermatocytes chromosomal aberrations were lower than simple high-dose group (P <0.01). The male mice pretreated with 0.05GyX line for 6h and then irradiated 2.0GyX line. The fertility rate in 9wk group was significantly higher than that in high dose group (P <0.01). It shows that low level of ionizing radiation not only has the effect of reducing the damage of genetic material of mice, but also can improve the fertility of mice irradiated by high dose.