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目的掌握辽宁省饮水型地方性氟中毒的流行现况,评价改水措施的防病效果。方法按病区分层抽取的85个病区村进行8~12岁儿童氟斑牙、16岁以上成人临床氟骨症的普查,采集饮用水和儿童尿样进行氟含量的检测。结果抽样病区8~12岁儿童氟斑牙检出率为16.74%,尿氟几何均值0.97 mg/L。8~12岁儿童氟斑牙检出率重病区高于中病区,中病区高于轻病区,未改水病区儿童尿氟水平明显高于改水病区。16岁以上人群临床氟骨症检出率为4.98%,随着年龄的增长氟骨症检出率逐渐升高。结论地方性氟中毒病情随着病区水氟含量的增高而逐渐加重。
Objective To understand the prevalence of endemic fluorosis in drinking water in Liaoning Province and to evaluate the preventive effect of water diversion measures. Methods Eighty-two wards of children aged 8-12 years with dental fluorosis and clinical skeletal fluorosis of adults over 16 years of age were surveyed in 85 ward villages stratified by ward. Drinking water and children’s urine samples were collected for fluorine content detection. Results The detection rate of dental fluorosis in children aged 8 ~ 12 years was 16.74% in sampled area, and the geometric mean urinary fluoride was 0.97 mg / L. The prevalence of dental fluorosis in children aged 8 ~ 12 years was higher than that in the disease-free area, and the prevalence in the ward was higher than that in the light-affected area. The urinary fluoride level in children with un-altered water-polluted area was significantly higher than that in the water-damaged area. The detection rate of clinical skeletal fluorosis in people above 16 years old was 4.98%, and the detection rate of skeletal fluorosis gradually increased with age. Conclusion The incidence of endemic fluorosis increased gradually with the increase of fluoride in the ward.