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人们使用多种方法处理血液制品,以求降低传染病毒性肝炎的危险。然而,现有的可以充分消除病毒的方法,却不能同时保持凝血因子的生物学活性。作者采用加热血液制品的方法,处理浓缩的人抗血友病因子(AHF,或因子Ⅷ),观察对去除肝炎病毒的作用。试验用6只黑猩猩,根据感染剂量的大小,分成两组,每组3只,一组注射300黑猩猩感染剂量单位(CID)的乙型肝炎病毒(HBV);另一组注射30,000CID的HBV,而两组的非甲非乙型肝炎病原体的浓度相同,AHF的量均为10ml。两组又各分两种情况注射感染原:给各组的两只黑猩猩注射的AHF
People use a variety of methods to treat blood products in order to reduce the risk of viral hepatitis. However, the existing methods that can fully eliminate the virus can not simultaneously maintain the biological activity of the clotting factor. The authors used a method of heating blood products to treat concentrated human anti-haemophilic factor (AHF, or factor VIII) to observe the effect on the removal of hepatitis virus. Six chimpanzees were divided into two groups according to the size of the infection dose. Each group consisted of 3 chickens injected with 300 chimpanzees infected with hepatitis C virus (HBV); another group injected with 30,000 CID of HBV, The two groups of non-A non-B hepatitis pathogens at the same concentration, AHF volume were 10ml. The two groups were injected in two different situations: the AHF injected with two chimpanzees in each group