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大量研究表明 ,线粒体在细胞凋亡与坏死这二种死亡形式中起重要作用。在神经元死亡中 ,根据最初损伤的程度不同 ,这二种死亡形式可以同时存在也可以相继发生。细胞的能量储备在这二种死亡形式中起重要作用。如果损伤程度相对轻微 ,ＡＴＰ保留 ,则发生凋亡 ;若损伤严重 ,ＡＴＰ
Numerous studies have shown that mitochondria play an important role in both the apoptotic and necrotic forms of death. In neuronal death, depending on the extent of the initial lesion, the two forms of death can occur simultaneously and one after the other. The energy reserve of cells plays an important role in these two forms of death. If the lesion is relatively mild, ATP is retained and apoptosis occurs; if severe, ATP