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本试验目的在于了解翠猴长期重度感染曼氏血吸虫后是否能产生人类样的肝或肠的病理损害,并观察在这种感染条件下宿主与寄生虫间的相互关系。共用雄性成年翠猴47只及雌性成年翠猴1只。48猴中的8只作为未感染的对照,另40只经皮肤感染波多黎各株曼氏血吸虫尾蚴400或600条。从感染600条尾蚴的翠猴中任意选择6～8只为一组,于感染后3、6及31个月剖杀,同时剖杀2～3只未感染正常翠猴作为对照。另在初次感染4或23个
The purpose of this experiment is to understand whether long-term chronic severe infections of Schistosoma mansoni can produce human-like liver or intestinal pathological damage and to observe the relationship between hosts and parasites under this infection condition. There were 47 males and 18 adult female adults. Eight of 48 monkeys were used as uninfected controls and the other 40 were skin-infected with 400 or 600 S. cercariae cercariae of Puerto Rico. Six to eight mice were randomly selected from the cercariae infected with 600 cercariae, and were killed at 3, 6 and 31 months after infection. At the same time, 2 to 3 unaffected normal children were killed as control. The other in the initial infection 4 or 23