中性粒细胞/淋巴细胞比值与2型糖尿病的关联研究

来源 :中华健康管理学杂志 | 被引量 : 0次 | 上传用户:buugly
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目的

探讨中性粒细胞/淋巴细胞比值(NLR)与2型糖尿病的关联。

方法

对象为2007至2013年在天津医科大学总医院健康管理中心接受健康体检的人群,其中男性49 861人,女性40 376人。2型糖尿病的诊断标准为,已经诊断糖尿病或空腹血糖≥7 mmol/L。统计方法采用多元logistic回归模型评估NLR五分位和2型糖尿病患病率的关联。

结果

2型糖尿病的患病率为5.1%。在男性,伴随着NLR值的增加,调整后2型糖尿病比值比(95%置信区间)分别为1.00(参考值),1.19(1.05,1.35),1.33(1.17, 1.50),1.28(1.13, 1.44)和1.34(1.19, 1.51)(趋势性P值<0.000 1)。女性:1.00(参考值),1.18(0.97, 1.45),1.02(0.83, 1.25),1.21 (0.99,1.48)和1.53(1.27, 1.86)(趋势性P值<0.000 1)。

结论

在男性和女性中,NLR与2型糖尿病的患病率均呈正相关。

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