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采用紫外分光光度法测定胃幽净中的盐酸小檗碱,分别对胃幽净胃内漂浮片和普通片的溶出度进行测定和比较。结果表明,胃内漂浮片溶出T50为1.18h,而普通片T50为3.16min在15min内全部溶解,胃内漂浮片具有缓释作用。
Ultraviolet spectrophotometry was used to determine berberine hydrochloride in Weijingjing, and the dissolution rates of gastric sedation tablets and ordinary tablets were measured and compared. The results showed that the T50 of gastric floating tablets was 1.18 h, while the T50 of ordinary tablets was 3.16 min. All dissolved within 15 min. The gastric floating tablets had a sustained release effect.